刘志华

生物物理学

中国科学院生物物理研究所

基本信息

刘志华,中科院生物物理所“青年千人计划”研究员,主要研究肠道黏膜特化细胞与肠道菌互作的分子机制及生理意义,采用无菌动物、悉生动物等模型研究肠道菌对肠道黏膜屏障的调控作用,旨在揭示肠道菌如何在多细胞水平上调控肠道多种细胞活动进而维持肠道稳态.刘志华研究员在Nature Immunology、Cell Research等重要国际期刊上发表多篇担任第一作者或通讯作者的论文,其中在肠道菌与宿主共生领域取得的相关研究成果作为封面文章发表在Nature Immunology上,Nature Review Immunology和Nature Immunology都有专文对该工作进行了深度解析;在分子水平揭示了LRRK2与炎症性肠炎发生的相关性的成果,作为封面文章发表在Nature Immunology上,被Science Signaling杂志编辑点评,Nature Immunology和Expert Rev Clin Immunol都有专文对该工作进行了深度解析.

科研成果

总发文数(篇)
0
总被引数(次)
0
H指数
0
篇均被引(次)
0
TOP1%高被引
0
TOP10%高被引
0
FWCI
0
国际合作发文数(篇)
0

成果分析

期刊发文数占比
重点学科匹配度: 论文历年发表情况; 合作发文情况; 文章被引情况

科研论文更多

Downregulation of retinoic acid receptor-β 2 -expression is linked to aberrant methylation in esophageal squamous-cell carcinoma cell lines
- 摘要：
  Aim: To study the role of hypermethylation in the loss of retinoic ac
- 作者：
  Liu Zhong-Min;Ding Fang;Zhang Li-Yong;Wu Min;Liu Zhi-Hua;Guo Ming-Zhou
- 刊名：
  World Journal of Gastroenterology
- 在线出版时间：
  2004
B23 regulates GADD45a nuclear translocation and contributes to GADD45a-induced cell cycle G2-M arrest
- 摘要：
  Gadd45a is an important player in cell cycle G2-M arrest in
- 作者：
  Gao Hua;Jin Shunqian;Song Yongmei;Fu Ming;Wang Minrong;Liu Zhihua;Wu Min;Zhan Qimin
- 刊名：
  Journal of Biological Chemistry
- 在线出版时间：
  2005
Allelic imbalance of chromosome 1q in esophageal squamous cell carcinomas from China: A novel region of allelic loss and significant association with differentiation
- 摘要：
  Our previous work has shown that a number of genes locating on 1q21 we
- 作者：
  Li Jie;Liu Zhongmin;Wang Mingrong;Zhan Qimin;Liu Zhihua;Wang Yunhai;Yu Zaicheng
- 刊名：
  Cancer Letters
- 在线出版时间：
  2005
In vivo reversal of multidrug resistance by transduction of human tumor necrosis factor-alpha into drug resistant cell line of choriocarcinoma
- 摘要：
  OBJECTIVE: To investigate in vivo reversal of multidrug resistance and
- 作者：
  Feng Feng-zhi;Xiang Yang;Cui Zhu-mei;Liu Zhi-hua;Yang Xiu-yu
- 刊名：
  Zhonghua Fu Chan Ke Za Zhi
- 在线出版时间：
  2003
5-Aza-2′-deoxycytidine induces retinoic acid receptor- β 2 demethylation and growth inhibition in esophageal squamous carcinoma cells
- 摘要：
  Esophageal squamous cell carcinoma (ESCC) is one of the most common t
- 作者：
  Liu Zhongmin;Zhang Liyong;Ding Fang;Li Jie;Li Wendong;Zhan Qimin;Wu Min;Liu Zhihua;Guo Mingzhou;Wang Yunhai;Yu Zaicheng
- 刊名：
  Cancer Letters
- 在线出版时间：
  2005
Prognostic significance of stomatin-like protein 2 overexpression in laryngeal squamous cell carcinoma: clinical, histologic, and immunohistochemistry analyses with tissue microarray
- 摘要：
  Stomatin-like protein 2 (SLP-2) is a novel cancer-related gene whose p
- 作者：
  Cao Wen-feng;Sun Bao-cun;Zhang Li-yong;Liu Zhi-hua;Liu Ming-bo;Tang Ping-zhang
- 刊名：
  Human Pathology
- 在线出版时间：
  2007

科创中国

刘志华

基本信息

科研成果

总发文数(篇)

总被引数(次)

H指数

篇均被引(次)

TOP1%高被引

TOP10%高被引

FWCI

国际合作发文数(篇)

成果分析

期刊发文数占比

重点学科匹配度

论文历年发表情况

合作发文情况

文章被引情况

科研论文更多

Downregulation of retinoic acid receptor-β 2 -expression is linked to aberrant methylation in esophageal squamous-cell carcinoma cell lines

B23 regulates GADD45a nuclear translocation and contributes to GADD45a-induced cell cycle G2-M arrest

Allelic imbalance of chromosome 1q in esophageal squamous cell carcinomas from China: A novel region of allelic loss and significant association with differentiation

In vivo reversal of multidrug resistance by transduction of human tumor necrosis factor-alpha into drug resistant cell line of choriocarcinoma

5-Aza-2′-deoxycytidine induces retinoic acid receptor- β 2 demethylation and growth inhibition in esophageal squamous carcinoma cells

Prognostic significance of stomatin-like protein 2 overexpression in laryngeal squamous cell carcinoma: clinical, histologic, and immunohistochemistry analyses with tissue microarray

友情链接

海外专利信息资源系统

省级中心站

科创中国

刘志华

基本信息

科研成果

总发文数(篇)

总被引数(次)

H指数

篇均被引(次)

TOP1%高被引

TOP10%高被引

FWCI

国际合作发文数(篇)

成果分析

期刊发文数占比

重点学科匹配度

论文历年发表情况

合作发文情况

文章被引情况

科研论文 更多

Downregulation of retinoic acid receptor-β 2 -expression is linked to aberrant methylation in esophageal squamous-cell carcinoma cell lines

B23 regulates GADD45a nuclear translocation and contributes to GADD45a-induced cell cycle G2-M arrest

Allelic imbalance of chromosome 1q in esophageal squamous cell carcinomas from China: A novel region of allelic loss and significant association with differentiation

In vivo reversal of multidrug resistance by transduction of human tumor necrosis factor-alpha into drug resistant cell line of choriocarcinoma

5-Aza-2′-deoxycytidine induces retinoic acid receptor- β 2 demethylation and growth inhibition in esophageal squamous carcinoma cells

Prognostic significance of stomatin-like protein 2 overexpression in laryngeal squamous cell carcinoma: clinical, histologic, and immunohistochemistry analyses with tissue microarray

友情链接

海外专利信息资源系统

省级中心站

科研论文更多