唐惠儒,男,1966年生,国家杰出青年科学基金获得者、英国皇家化学会会士、复旦大学教授。1986年获西北轻工业学院(现陕西科技大学)学士学位,1994年获伦敦大学博士学位。1992-2000年英国BBSRC食品研究所Research Scientist、Senior Scientist。2001-05年英国帝国理工学院生物医学部Senior Scientist。2005-14年中科院武汉物数所研究员、博士生导师、研究部副主任、中科院生物磁共振分析重点实验室主任。2014年加盟复旦大学生命科学学院。曾任英国NHS、科技部973及蛋白质重大计划等评审专家、J Proteome Res编委
研究领域
研究代谢物结构与功能30年,正发展高通量超灵敏代谢组学技术、代谢组与转录组/蛋白质组/微生物组等数据整合技术,研究肥胖等重大疾病发生发展的代谢组基础
近期论文
1. J.H. Xue, et al, “A vitamin-C-derived DNA modification catalysed by an algal TET homologue”, Nature, 569:581–585, 2019.
2. C.X. Liu, et al, “Metabolic changes of Fusarium graminearum induced by TPS gene deletion”. J Proteome Res, doi.org/10.1021/acs.jproteome.9b00259, 2019
3. H. Lin, et al, “Alterations of bile acids and gut microbiota in obesity induced by high fat diet in rat mode”, J Agric Food Chem, 67:3624-3632. 2019
4. L.M. Zhang, et al, “Metabolomics reveals that dietary ferulic acid and quercetin modulate metabolic homeostasis in rats”, J Agric Food Chem, 66, 1723−1731, 2018
5. J.B. Gou, et al, “Discovery of a non-stereoselective cytochrome P450 catalyzing either 8α- or 8β- hydroxylation of germacrene A acid from the Chinese medicinal plant, Inula hupehensis”, Plant J, 93:92-106, 2018.
6. F.F. Chen, et al, “Combined metabonomic and quantitative RT-PCR analyses revealed metabolic reprogramming associated with Fusarium graminearum resistance in transgenic Arabidopsis thaliana”, Frontiers Plant Science, 8:2177, 2018.
7. X.C. He, et al “Influence of genotype and environment on volatile profile of Valerianae jatamansi Rhizoma et Radix”, Front Plant Sci, 9:1003, 2018.
8. Q. Wang, et al, “Interspecies developmental differences in metabonomic phenotypes of Lycium ruthenicum and L. barbarum fruits”, J Proteome Res, 17:3223-3236, 2018
9. Q.F. Wan, et al, "Quantitative 13C traces of glucose fate in hepatitis B virus infected hepatocytes", Anal Chem, 89:3293–3299, 2017
10. J. Wang, et al, "Simultaneous quantification of amino metabolites in m